Being the third most common non-skin cancer and the third leading cause of cancer-related mortality in men and women in the United States, colorectal cancer can be a devastating disease. Nonetheless, according to the latest statistics from NCI covering the period 2006 to 2010, death rates continue to decline, due in part to improved treatments, and in part to colorectal cancer screening options that are proven to reduce mortality and that have gained acceptance by the public.